ITGA3 antibody (AA 168-276)
Quick Overview for ITGA3 antibody (AA 168-276) (ABIN7156434)
Target
See all ITGA3 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 168-276
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Cross-Reactivity
- Human
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Purification
- >95%, Protein G purified
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Immunogen
- Recombinant Human Integrin alpha-3 protein (168-276AA)
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Isotype
- IgG
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Application Notes
- Recommended dilution: IHC:1:200-1:500, IF:1:50-1:200,
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
Preservative
- ProClin
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Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C,-80 °C
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Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- ITGA3 (Integrin, alpha 3 (ITGA3))
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Alternative Name
- ITGA3
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Background
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Background: Integrin alpha-3/beta-1 is a receptor for fibronectin, laminin, collagen, epiligrin, thrombospondin and CSPG4. Integrin alpha-3/beta-1 provides a docking site for FAP (seprase) at invadopodia plasma membranes in a collagen-dependent manner and hence may participate in the adhesion, formation of invadopodia and matrix degradation processes, promoting cell invasion. Alpha-3/beta-1 may mediate with LGALS3 the stimulation by CSPG4 of endothelial cells migration.
Aliases: AA407068 antibody, Antigen identified by monoclonal antibody J143 antibody, CD49 antigen like family member C antibody, CD49 antigen-like family member C antibody, CD49c antibody, CD49c antigen antibody, FLJ34631 antibody, FLJ34704 antibody, FRP 2 antibody, FRP-2 antibody, FRP2 antibody, Galactoprotein B3 antibody, GAP B3 antibody, GAPB3 antibody, Integrin alpha 3 antibody, Integrin alpha-3 light chain antibody, Integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) antibody, ITA3_HUMAN antibody, ITGA 3 antibody, Itga3 antibody, MSK18 antibody, VCA 2 antibody, VCA2 antibody, Very late activation protein 3 receptor alpha 3 subunit antibody, VL3A antibody, VLA 3 alpha chain antibody, VLA 3 subunit alpha antibody, VLA-3 subunit alpha antibody, VLA3a antibody
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UniProt
- P26006
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Pathways
- CXCR4-mediated Signaling Events, Integrin Complex
Target
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