ITGA6 antibody (AA 625-866)

Catalog No. ABIN7156446

The Rabbit Polyclonal anti-ITGA6 antibody has been validated for WB, ELISA and IF. It is suitable to detect ITGA6 in samples from Human.

Quick Overview for ITGA6 antibody (AA 625-866) (ABIN7156446)

Target: ITGA6 (Integrin, alpha 6 (ITGA6))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ITGA6 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Product Details anti-ITGA6 Antibody

Binding Specificity: AA 625-866

Cross-Reactivity: Human, Mouse, Rat

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Integrin alpha-6 protein (625-866AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:500-1:5000, IF:1:200-1:500,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for ITGA6

Target: ITGA6 (Integrin, alpha 6 (ITGA6))

Alternative Name: ITGA6

Background:

Background: Integrin alpha-6/beta-1 is a receptor for laminin on platelets. Integrin alpha-6/beta-4 is a receptor for laminin in epithelial cells and it plays a critical structural role in the hemidesmosome (By similarity). ITGA6:ITGB4 binds to NRG1 (via EGF domain) and this binding is essential for NRG1-ERBB signaling (PubMed:20682778). ITGA6:ITGB4 binds to IGF1 and this binding is essential for IGF1 signaling (PubMed:22351760).

Aliases: Alpha6p antibody, CD49 antigen-like family member F antibody, CD49f antibody, Integrin alpha6B antibody, Integrin, alpha 6 antibody, ITA6_HUMAN antibody, ITGA6 antibody, ITGA6B antibody, Processed integrin alpha-6 antibody, VLA 6 antibody, VLA-6 antibody

UniProt: P23229

Pathways: CXCR4-mediated Signaling Events, Brown Fat Cell Differentiation, Integrin Complex