IL29 antibody (AA 21-200) (Biotin)
Quick Overview for IL29 antibody (AA 21-200) (Biotin) (ABIN7156609)
Target
See all IL29 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 21-200
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Cross-Reactivity
- Human
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Purification
- >95%, Protein G purified
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Immunogen
- Recombinant Human Interferon lambda-1 protein (21-200AA)
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Isotype
- IgG
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
Preservative
- ProClin
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Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C,-80 °C
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Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- IL29 (Interleukin 29 (IL29))
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Alternative Name
- IFNL1
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Background
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Background: Cytokine with antiviral, antitumour and immunomodulatory activities. Plays a critical role in the antiviral host defense, predominantly in the epithelial tissues. Acts as a ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IFNLR1, and receptor engagement leads to the activation of the JAK/STAT signaling pathway resulting in the expression of IFN-stimulated genes (ISG), which mediate the antiviral state. Has a restricted receptor distribution and therefore restricted targets: is primarily active in epithelial cells and this cell type-selective action is because of the epithelial cell-specific expression of its receptor IFNLR1. Exerts an immunomodulatory effect by up-regulating MHC class I antigen expression.
Aliases: IFNL1 antibody, IL29 antibody, ZCYTO21Interferon lambda-1 antibody, IFN-lambda-1 antibody, Cytokine Zcyto21 antibody, Interleukin-29 antibody, IL-29 antibody
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UniProt
- Q8IU54
Target
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