IFITM2 antibody (AA 1-56) (HRP)

Catalog No. ABIN7156686

The Rabbit Polyclonal anti-IFITM2 antibody has been validated for ELISA. It is suitable to detect IFITM2 in samples from Human.

Quick Overview for IFITM2 antibody (AA 1-56) (HRP) (ABIN7156686)

Target: IFITM2 (Interferon Induced Transmembrane Protein 2 (IFITM2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IFITM2 antibody is conjugated to HRP

Application: ELISA

Product Details anti-IFITM2 Antibody (HRP)

Binding Specificity: AA 1-56

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Interferon-induced transmembrane protein 2 protein (1-56AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for IFITM2

Target: IFITM2 (Interferon Induced Transmembrane Protein 2 (IFITM2))

Alternative Name: IFITM2

Background:

Background: IFN-induced antiviral protein which inhibits the entry of viruses to the host cell cytoplasm, permitting endocytosis, but preventing subsequent viral fusion and release of viral contents into the cytosol. Active against multiple viruses, including influenza A virus, SARS coronavirus (SARS-CoV), Marburg virus (MARV), Ebola virus (EBOV), Dengue virus (DNV), West Nile virus (WNV), human immunodeficiency virus type 1 (HIV-1) and vesicular stomatitis virus (VSV). Can inhibit: influenza virus hemagglutinin protein-mediated viral entry, MARV and EBOV GP1,2-mediated viral entry, SARS-CoV S protein-mediated viral entry and VSV G protein-mediated viral entry. Induces cell cycle arrest and mediates apoptosis by caspase activation and in p53-independent manner.

Aliases: IFITM2Interferon-induced transmembrane protein 2 antibody, Dispanin subfamily A member 2c antibody, DSPA2c antibody, Interferon-inducible protein 1-8D antibody

UniProt: Q01629