IL31RA antibody (AA 1-300)

Catalog No. ABIN7156889

This Rabbit Polyclonal antibody specifically detects IL31RA in ELISA and IHC. It exhibits reactivity toward Human.

Quick Overview for IL31RA antibody (AA 1-300) (ABIN7156889)

Target: IL31RA (Interleukin 31 Receptor A (IL31RA))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IL31RA antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Product Details anti-IL31RA Antibody

Binding Specificity: AA 1-300

Cross-Reactivity: Human

Purification: Antigen Affinity Purified

Immunogen: Recombinant Human Interleukin-31 receptor subunit alpha protein (1-300AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for IL31RA

Target: IL31RA (Interleukin 31 Receptor A (IL31RA))

Alternative Name: IL31RA

Background:

Background: Associates with OSMR to form the interleukin-31 receptor which activates STAT3 and to a lower extent STAT1 and STAT5 (PubMed:11877449, PubMed:14504285, PubMed:15627637, PubMed:15194700). May function in skin immunity (PubMed:15184896). Mediates IL31-induced itch, probably in a manner dependent on cation channels TRPA1 and TRPV1 (By similarity). Positively regulates numbers and cycling status of immature subsets of myeloid progenitor cells in bone marrow in vivo and enhances myeloid progenitor cell survival in vitro (By similarity).

Aliases: Class I cytokine receptor antibody, CRL 3 antibody, CRL antibody, CRL3 antibody, Cytokine receptor like 3 antibody, Cytokine receptor-like 3 antibody, GLM R antibody, GLM-R antibody, GLMR antibody, Gp130 like monocyte receptor antibody, GP130 like receptor antibody, Gp130-like monocyte receptor antibody, Gp130-like receptor antibody, GPL antibody, HGLM R antibody, HGLM-R antibody, HGLMR antibody, IL 31 receptor subunit alpha antibody, IL 31R subunit alpha antibody, IL 31RA antibody, IL-31 receptor subunit alpha antibody, IL-31R subunit alpha antibody, IL-31R-alpha antibody, IL-31RA antibody, IL31 receptor subunit alpha antibody, IL31R subunit alpha antibody, IL31R_HUMAN antibody, IL31RA antibody, Interleukin 31 receptor A antibody, interleukin 31 receptor subunit alpha antibody, Interleukin-31 receptor subunit alpha antibody, MGC125346 antibody, PLCA 2 antibody, PLCA2 antibody, PRO21384 antibody, Soluble type I cytokine receptor CRL3 antibody, ZcytoR17 antibody

UniProt: Q8NI17