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LGI1 antibody (AA 35-285)

This Rabbit Polyclonal antibody specifically detects LGI1 in IHC and ELISA. It exhibits reactivity toward Human.
Catalog No. ABIN7158044

Quick Overview for LGI1 antibody (AA 35-285) (ABIN7158044)

Target

See all LGI1 Antibodies
LGI1 (Leucine-Rich, Glioma Inactivated 1 (LGI1))

Reactivity

  • 42
  • 27
  • 16
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Human

Host

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Rabbit

Clonality

  • 28
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Polyclonal

Conjugate

  • 22
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This LGI1 antibody is un-conjugated

Application

  • 50
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  • 5
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Immunohistochemistry (IHC), ELISA
  • Binding Specificity

    • 17
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    AA 35-285

    Purpose

    LGI1 Antibody

    Purification

    Antigen Affinity Purified

    Immunogen

    Recombinant Human Leucine-rich glioma-inactivated protein 1 protein (35-285AA)

    Isotype

    IgG
  • Application Notes

    Optimal working dilution should be determined by the investigator.

    Restrictions

    For Research Use only
  • Format

    Liquid

    Buffer

    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

    Preservative

    Sodium azide

    Precaution of Use

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Storage

    -20 °C,-80 °C

    Storage Comment

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target

    LGI1 (Leucine-Rich, Glioma Inactivated 1 (LGI1))

    Alternative Name

    LGI1

    Background

    Background: Regulates voltage-gated potassium channels assembled from KCNA1, KCNA4 and KCNAB1. It slows down channel inactivation by precluding channel closure mediated by the KCNAB1 subunit. Ligand for ADAM22 that positively regulates synaptic transmission mediated by AMPA-type glutamate receptors (By similarity). Plays a role in suppressing the production of MMP1/3 through the phosphatidylinositol 3-kinase/ERK pathway. May play a role in the control of neuroblastoma cell survival.

    Aliases: ADLTE antibody, ADPAEF antibody, ADPEAF antibody, Epitempin 1 antibody, EPITEMPIN antibody, Epitempin-1 antibody, EPT antibody, ETL1 antibody, IB1099 antibody, leucine rich glioma inactivated 1 antibody, Leucine rich glioma-inactivated protein 1 antibody, Leucine-rich glioma-inactivated protein 1 antibody, LGI1 antibody, LGI1_HUMAN antibody, OTTHUMP00000020121 antibody, OTTHUMP00000020122 antibody

    UniProt

    O95970
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