LILRB1 antibody (AA 483-650)
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- Target See all LILRB1 Antibodies
- LILRB1 (Leukocyte Immunoglobulin-Like Receptor, Subfamily B (With TM and ITIM Domains), Member 1 (LILRB1))
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Binding Specificity
- AA 483-650
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This LILRB1 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
- Cross-Reactivity
- Human, Rat
- Purification
- >95%, Protein G purified
- Immunogen
- Recombinant Human Leukocyte immunoglobulin-like receptor subfamily B member 1 protein (483-650AA)
- Isotype
- IgG
- Top Product
- Discover our top product LILRB1 Primary Antibody
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- Application Notes
- Recommended dilution: WB:1:500-1:5000, IHC:1:200-1:500, IF:1:50-1:200,
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- LILRB1 (Leukocyte Immunoglobulin-Like Receptor, Subfamily B (With TM and ITIM Domains), Member 1 (LILRB1))
- Alternative Name
- LILRB1 (LILRB1 Products)
- Synonyms
- CD85J antibody, ILT-2 antibody, ILT2 antibody, LIR-1 antibody, LIR1 antibody, MIR-7 antibody, MIR7 antibody, leukocyte immunoglobulin like receptor B1 antibody, LILRB1 antibody
- Background
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Background: Receptor for class I MHC antigens. Recognizes a broad spectrum of HLA-A, HLA-B, HLA-C and HLA-G alleles. Receptor for H301/UL18, a human cytomegalovirus class I MHC homolog. Ligand binding results in inhibitory signals and down-regulation of the immune response. Engagement of LILRB1 present on natural killer cells or T-cells by class I MHC molecules protects the target cells from lysis. Interaction with HLA-B or HLA-E leads to inhibition of the signal triggered by FCER1A and inhibits serotonin release. Inhibits FCGR1A-mediated phosphorylation of cellular proteins and mobilization of intracellular calcium ions.
Aliases: CD85 antibody, CD85 antigen antibody, CD85 antigen like family member J antibody, CD85 antigen-like family member J antibody, CD85j antibody, CD85j antigen antibody, Ig like transcript 2 antibody, ILT 2 antibody, ILT-2 antibody, ILT2 antibody, immunoglobulin like transcript 2 antibody, Immunoglobulin-like transcript 2 antibody, leukocyte Ig like receptor 1 antibody, Leukocyte immunoglobulin like receptor 1 antibody, leukocyte immunoglobulin like receptor subfamily B member 1 antibody, Leukocyte immunoglobulin like receptor subfamily B member 1 precursor antibody, leukocyte immunoglobulin like receptor subfamily B member 1 soluble isoform antibody, leukocyte immunoglobulin like receptor, subfamily B, member 1 antibody, Leukocyte immunoglobulin-like receptor 1 antibody, Leukocyte immunoglobulin-like receptor subfamily B member 1 antibody, leukocyte immunoglobulin-like receptor subfamily B member 1 soluble isoform antibody, leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1 antibody, LILRB1 antibody, LIR 1 antibody, LIR-1 antibody, LIR1 antibody, LIRB1_HUMAN antibody, MIR 7 antibody, MIR-7 antibody, MIR7 antibody, Monocyte/macrophage immunoglobulin like receptor 7 antibody, Monocyte/macrophage immunoglobulin-like receptor 7 antibody, PIR B antibody, PIRB antibody
- UniProt
- Q8NHL6
- Pathways
- Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
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