LMCD1 antibody (AA 105-268)

Catalog No. ABIN7158336

The Rabbit Polyclonal anti-LMCD1 antibody has been validated for ELISA, IHC and IF. It is suitable to detect LMCD1 in samples from Human.

Quick Overview for LMCD1 antibody (AA 105-268) (ABIN7158336)

Target: LMCD1 (LIM and Cysteine-Rich Domains 1 (LMCD1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LMCD1 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-LMCD1 Antibody

Binding Specificity: AA 105-268

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human LIM and cysteine-rich domains protein 1 protein (105-268AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:200-1:500, IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for LMCD1

Target: LMCD1 (LIM and Cysteine-Rich Domains 1 (LMCD1))

Alternative Name: LMCD1

Background:

Background: Transcriptional cofactor that restricts GATA6 function by inhibiting DNA-binding, resulting in repression of GATA6 transcriptional activation of downstream target genes. Represses GATA6-mediated trans activation of lung- and cardiac tissue-specific promoters. Inhibits DNA-binding by GATA4 and GATA1 to the cTNC promoter (By similarity). Plays a critical role in the development of cardiac hypertrophy via activation of calcineurin/nuclear factor of activated T-cells signaling pathway.

Aliases: Dyxin antibody, LIM and cysteine rich domains 1 antibody, LIM and cysteine rich domains protein 1 antibody, LIM and cysteine-rich domains protein 1 antibody, LMCD1 antibody, LMCD1_HUMAN antibody

UniProt: Q9NZU5