DBT antibody (AA 140-259) (HRP)

Catalog No. ABIN7158425

This Rabbit Polyclonal antibody specifically detects DBT in ELISA. It exhibits reactivity toward Human.

Quick Overview for DBT antibody (AA 140-259) (HRP) (ABIN7158425)

Target: DBT (Dihydrolipoamide Branched Chain Transacylase E2 (DBT))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DBT antibody is conjugated to HRP

Application: ELISA

Product Details anti-DBT Antibody (HRP)

Binding Specificity: AA 140-259

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial protein (140-259AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for DBT

Target: DBT (Dihydrolipoamide Branched Chain Transacylase E2 (DBT))

Alternative Name: DBT

Background:

Background: The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). Within this complex, the catalytic function of this enzyme is to accept, and to transfer to coenzyme A, acyl groups that are generated by the branched-chain alpha-keto acid decarboxylase component.

Aliases: DBT antibody, BCATE2 antibody, Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex antibody, mitochondrial antibody, EC 2.3.1.168 antibody, 52 kDa mitochondrial autoantigen of primary biliary cirrhosis antibody, Branched chain 2-oxo-acid dehydrogenase complex component E2 antibody, BCOADC-E2 antibody, Branched-chain alpha-keto acid dehydrogenase complex component E2 antibody, BCKAD-E2 antibody, BCKADE2 antibody, Dihydrolipoamide acetyltransferase component of branched-chain alpha-keto acid dehydrogenase complex antibody, Dihydrolipoamide branched chain transacylase antibody, Dihydrolipoyllysine-residue antibody, 2-methylpropanoyl)transferase antibody

UniProt: P11182