DCP2 antibody (AA 1-240)

Catalog No. ABIN7158861

The Rabbit Polyclonal anti-DCP2 antibody has been validated for WB, ELISA and IHC. It is suitable to detect DCP2 in samples from Human.

Quick Overview for DCP2 antibody (AA 1-240) (ABIN7158861)

Target: DCP2 (DCP2 Decapping Enzyme Homolog (DCP2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DCP2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-DCP2 Antibody

Binding Specificity: AA 1-240

Cross-Reactivity: Human

Purification: Antigen Affinity Purified

Immunogen: Recombinant Human m7GpppN-mRNA hydrolase protein (1-240AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:200-1:1000, IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for DCP2

Target: DCP2 (DCP2 Decapping Enzyme Homolog (DCP2))

Alternative Name: DCP2

Background:

Background: Decapping metalloenzyme that catalyzes the cleavage of the cap structure on mRNAs. Removes the 7-methyl guanine cap structure from mRNA molecules, yielding a 5\\\'-phosphorylated mRNA fragment and 7m-GDP. Necessary for the degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay. Plays a role in replication-dependent histone mRNA degradation. Has higher activity towards mRNAs that lack a poly(A) tail. Has no activity towards a cap structure lacking an RNA moiety.

Aliases: DCP2 antibody, DCP2 decapping enzyme homolog (S. cerevisiae) antibody, DCP2, S. cerevisiae, homolog of antibody, DCP2_HUMAN antibody, decapping enzyme 2, S. cerevisiae, homolog of antibody, decapping enzyme homolog (S. cerevisiae) antibody, FLJ33245 antibody, hDpc antibody, m7GpppN-mRNA hydrolase antibody, mRNA decapping enzyme 2 antibody, mRNA-decapping enzyme 2 antibody, Nucleoside diphosphate-linked moiety X motif 20 antibody, nudix (nucleoside diphosphate linked moiety X)-type motif 20 antibody, Nudix motif 20 antibody, NUDT20 antibody

UniProt: Q8IU60