MR1 antibody (AA 150-253)

Catalog No. ABIN7158927

The Rabbit Polyclonal anti-MR1 antibody has been validated for ELISA, WB, IHC and IF. It is suitable to detect MR1 in samples from Human.

Quick Overview for MR1 antibody (AA 150-253) (ABIN7158927)

Target: MR1 (Major Histocompatibility Complex, Class I-Related (MR1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MR1 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-MR1 Antibody

Binding Specificity: AA 150-253

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Major histocompatibility complex class I-related gene protein (150-253AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for MR1

Target: MR1 (Major Histocompatibility Complex, Class I-Related (MR1))

Alternative Name: MR1

Background:

Background: Antigen-presenting molecule specialized in presenting microbial vitamin B metabolites. Involved in the development and expansion of a small population of T-cells expressing an invariant T-cell receptor alpha chain called mucosal-associated invariant T-cells (MAIT). MAIT lymphocytes are preferentially located in the gut lamina propria and therefore may be involved in monitoring commensal flora or serve as a distress signal. Expression and MAIT cell recognition seem to be ligand-dependent.

Aliases: Class I histocompatibility antigen like protein antibody, Class I histocompatibility antigen-like protein antibody, HLALS antibody, HMR1_HUMAN antibody, Major histocompatibility complex class I like sequence antibody, Major histocompatibility complex class I related antibody, Major histocompatibility complex class I related gene protein antibody, Major histocompatibility complex class I related isoform CRA a antibody, Major histocompatibility complex class I related isoform CRA c antibody, Major histocompatibility complex class I related isoform CRA d antibody, Major histocompatibility complex class I-related gene protein antibody, MHC class I like antigen MR 1 antibody, MHC class I like antigen MR1 antibody, MHC class I related gene protein antibody, MHC class I related protein 1 isoform B antibody, MHC class I related protein 1 isoform C antibody, MHC class I-related gene protein antibody, MR 1 antibody, Mr1 antibody, Mr1 protein antibody, MR1B antibody, MR1C antibody

UniProt: Q95460

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints