MASP1 antibody (AA 20-699) (FITC)

Catalog No. ABIN7158972

The Rabbit Polyclonal anti-MASP1 antibody has been validated for . It is suitable to detect MASP1 in samples from Human.

Quick Overview for MASP1 antibody (AA 20-699) (FITC) (ABIN7158972)

Target: MASP1 (Mannan-Binding Lectin Serine Peptidase 1 (MASP1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MASP1 antibody is conjugated to FITC

Application: Please inquire

Product Details anti-MASP1 Antibody (FITC)

Binding Specificity: AA 20-699

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Mannan-binding lectin serine protease 1 protein (20-699AA)

Isotype: IgG

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for MASP1

Target: MASP1 (Mannan-Binding Lectin Serine Peptidase 1 (MASP1))

Alternative Name: MASP1

Background:

Background: Functions in the lectin pathway of complement, which performs a key role in innate immunity by recognizing pathogens through patterns of sugar moieties and neutralizing them. The lectin pathway is triggered upon binding of mannan-binding lectin (MBL) and ficolins to sugar moieties which leads to activation of the associated proteases MASP1 and MASP2. Functions as an endopeptidase and may activate MASP2 or C2 or directly activate C3 the key component of complement reaction. Isoform 2 may have an inhibitory effect on the activation of the lectin pathway of complement or may cleave IGFBP5.

Aliases: MASP1 antibody, CRARF antibody, CRARF1 antibody, PRSS5Mannan-binding lectin serine protease 1 antibody, EC 3.4.21.- antibody, Complement factor MASP-3 antibody, Complement-activating component of Ra-reactive factor antibody, Mannose-binding lectin-associated serine protease 1 antibody, MASP-1 antibody, Mannose-binding protein-associated serine protease antibody, Ra-reactive factor serine protease p100 antibody, RaRF antibody, Serine protease 5) [Cleaved into: Mannan-binding lectin serine protease 1 heavy chain, Mannan-binding lectin serine protease 1 light chain] antibody

UniProt: P48740

Pathways: Complement System