MED22 antibody (AA 2-140)
Quick Overview for MED22 antibody (AA 2-140) (ABIN7159124)
Target
See all MED22 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 2-140
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Cross-Reactivity
- Human
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Purification
- >95%, Protein G purified
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Immunogen
- Recombinant Human Mediator of RNA polymerase II transcription subunit 22 protein (2-140AA)
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Isotype
- IgG
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Application Notes
- Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
Preservative
- ProClin
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Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C,-80 °C
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Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- MED22 (Mediator Complex Subunit 22 (MED22))
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Alternative Name
- MED22
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Background
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Background: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
Aliases: MED22 antibody, SURF5Mediator of RNA polymerase II transcription subunit 22 antibody, Mediator complex subunit 22 antibody, Surfeit locus protein 5 antibody, Surf-5 antibody
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UniProt
- Q15528
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Pathways
- Regulation of Lipid Metabolism by PPARalpha
Target
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