MAGED1 antibody (AA 579-778)

Catalog No. ABIN7159294

This anti-MAGED1 antibody is a Rabbit Polyclonal antibody detecting MAGED1 in WB, IHC and ELISA. Suitable for Human.

Quick Overview for MAGED1 antibody (AA 579-778) (ABIN7159294)

Target: MAGED1 (Melanoma Antigen Family D, 1 (MAGED1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAGED1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-MAGED1 Antibody

Binding Specificity: AA 579-778

Cross-Reactivity: Human

Purification: Antigen Affinity Purified

Immunogen: Recombinant Human Melanoma-associated antigen D1 protein (579-778AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for MAGED1

Target: MAGED1 (Melanoma Antigen Family D, 1 (MAGED1))

Alternative Name: MAGED1

Background:

Background: Involved in the apoptotic response after nerve growth factor (NGF) binding in neuronal cells. Inhibits cell cycle progression, and facilitates NGFR-mediated apoptosis. May act as a regulator of the function of DLX family members. May enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzyme (E2) at the E3:substrate complex. Plays a role in the circadian rythm regulation. May act as RORA co-regulator, modulating the expression of core clock genes such as ARNTL/BMAL1 and NFIL3, induced, or NR1D1, repressed.

Aliases: DLXIN 1 antibody, MAGD1_HUMAN antibody, MAGE D1 antigen antibody, MAGE tumor antigen CCF antibody, MAGE-D1 antigen antibody, Maged1 antibody, Melanoma antigen family D 1 antibody, Melanoma associated antigen D1 antibody, Melanoma-associated antigen D1 antibody, Neurotrophin receptor interacting MAGE homolog antibody, Neurotrophin receptor-interacting MAGE homolog antibody, NRAGE antibody, PP2250 antibody

UniProt: Q9Y5V3

Pathways: Neurotrophin Signaling Pathway