TRABD2B antibody (AA 195-405) (Biotin)

Catalog No. ABIN7159478

This Rabbit Polyclonal antibody specifically detects TRABD2B in ELISA. It exhibits reactivity toward Human.

Quick Overview for TRABD2B antibody (AA 195-405) (Biotin) (ABIN7159478)

Target: TRABD2B (TraB Domain Containing 2B (TRABD2B))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRABD2B antibody is conjugated to Biotin

Application: ELISA

Product Details anti-TRABD2B Antibody (Biotin)

Binding Specificity: AA 195-405

Cross-Reactivity: Human

Purification: Antigen Affinity Purified

Immunogen: Recombinant Human Metalloprotease TIKI2 protein (195-405AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for TRABD2B

Target: TRABD2B (TraB Domain Containing 2B (TRABD2B))

Alternative Name: TRABD2B

Background:

Background: Metalloprotease that acts as a negative regulator of the Wnt signaling pathway by mediating the cleavage of the 8 N-terminal residues of a subset of Wnt proteins. Following cleavage, Wnt proteins become oxidized and form large disulfide-bond oligomers, leading to their inactivation. Able to cleave WNT3A, WNT5, but not WNT11. Required for head formation.

Aliases: TRABD2B antibody, HKAT antibody, TIKI2 antibody, Metalloprotease TIKI2 antibody, EC 3.4.-.- antibody, Heart antibody, kidney and adipose-enriched transmembrane protein homolog antibody, TRAB domain-containing protein 2B antibody

UniProt: A6NFA1