TRABD2B antibody (AA 195-405) (FITC)
Quick Overview for TRABD2B antibody (AA 195-405) (FITC) (ABIN7159479)
Target
Reactivity
Host
Clonality
Conjugate
Application
-
-
Binding Specificity
- AA 195-405
-
Cross-Reactivity
- Human
-
Purification
- Antigen Affinity Purified
-
Immunogen
- Recombinant Human Metalloprotease TIKI2 protein (195-405AA)
-
Isotype
- IgG
-
-
-
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Buffer
-
Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
Preservative
- ProClin
-
Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Storage
- -20 °C,-80 °C
-
Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
-
-
- TRABD2B (TraB Domain Containing 2B (TRABD2B))
-
Alternative Name
- TRABD2B
-
Background
-
Background: Metalloprotease that acts as a negative regulator of the Wnt signaling pathway by mediating the cleavage of the 8 N-terminal residues of a subset of Wnt proteins. Following cleavage, Wnt proteins become oxidized and form large disulfide-bond oligomers, leading to their inactivation. Able to cleave WNT3A, WNT5, but not WNT11. Required for head formation.
Aliases: TRABD2B antibody, HKAT antibody, TIKI2 antibody, Metalloprotease TIKI2 antibody, EC 3.4.-.- antibody, Heart antibody, kidney and adipose-enriched transmembrane protein homolog antibody, TRAB domain-containing protein 2B antibody
-
UniProt
- A6NFA1
Target
-