CHCHD3 antibody (AA 1-227)

Catalog No. ABIN7159686

The Rabbit Polyclonal anti-CHCHD3 antibody has been validated for WB, IHC and ELISA. It is suitable to detect CHCHD3 in samples from Human.

Quick Overview for CHCHD3 antibody (AA 1-227) (ABIN7159686)

Target: CHCHD3 (Coiled-Coil-Helix-Coiled-Coil-Helix Domain Containing 3 (CHCHD3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CHCHD3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-CHCHD3 Antibody

Binding Specificity: AA 1-227

Cross-Reactivity: Human, Mouse

Purification: Antigen Affinity Purified

Immunogen: Recombinant Human MICOS complex subunit MIC19 protein (1-227AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for CHCHD3

Target: CHCHD3 (Coiled-Coil-Helix-Coiled-Coil-Helix Domain Containing 3 (CHCHD3))

Alternative Name: CHCHD3

Background:

Background: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. Has also been shown to function as a transcription factor which binds to the BAG1 promoter and represses BAG1 transcription. Plays an important role in the maintenance of the MICOS complex stability and the mitochondrial cristae morphology (PubMed:25781180).

Aliases: CHCH3_HUMAN antibody, CHCHD 3 antibody, Chchd3 antibody, Coiled coil helix coiled coil helix domain containing 3 antibody, Coiled coil helix coiled coil helix domain containing protein 3 mitochondrial antibody, Coiled-coil-helix-coiled-coil-helix domain-containing protein 3 antibody, FLJ20420 antibody, MINOS3 antibody, mitochondrial antibody, Mitochondrial inner membrane organizing system 3 antibody, PPP1R22 antibody, Protein phosphatase 1 regulatory subunit 22 antibody

UniProt: Q9NX63