MCRS1 antibody (AA 1-138) (HRP)

Catalog No. ABIN7159741

This anti-MCRS1 antibody is a Rabbit Polyclonal antibody detecting MCRS1 in ELISA. Suitable for Human.

Quick Overview for MCRS1 antibody (AA 1-138) (HRP) (ABIN7159741)

Target: MCRS1 (Microspherule Protein 1 (MCRS1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MCRS1 antibody is conjugated to HRP

Application: ELISA

Product Details anti-MCRS1 Antibody (HRP)

Binding Specificity: AA 1-138

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Microspherule protein 1 protein (1-138AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for MCRS1

Target: MCRS1 (Microspherule Protein 1 (MCRS1))

Alternative Name: MCRS1

Background:

Background: Modulates the transcription repressor activity of DAXX by recruiting it to the nucleolus (PubMed:11948183). As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues (PubMed:20018852). Putative regulatory component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair. May also be an inhibitor of TERT telomerase activity (PubMed:15044100). Binds to G-quadruplex structures in mRNA (PubMed:16571602). Binds to RNA homopolymer poly(G) and poly(U) (PubMed:16571602).

Aliases: 58 kDa microspherule protein antibody, Cell cycle regulated factor (78 kDa) antibody, Cell cycle regulated factor p78 antibody, Cell cycle-regulated factor p78 antibody, ICP22BP antibody, INO80 complex subunit J antibody, MCRS 1 antibody, MCRS 2 antibody, MCRS1 antibody, MCRS1_HUMAN antibody, MCRS2 antibody, Microspherule protein 1 antibody, MSP 58 antibody, MSP58 antibody, p78 antibody

UniProt: Q96EZ8