C20orf72 antibody (AA 81-260) (HRP)
Quick Overview for C20orf72 antibody (AA 81-260) (HRP) (ABIN7159877)
Target
Reactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 81-260
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Purpose
- MGME1 Antibody, HRP conjugated
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Purification
- Protein G purified
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Purity
- >95 %
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Immunogen
- Recombinant Human Mitochondrial genome maintenance exonuclease 1 protein (81-260AA)
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Isotype
- IgG
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anti-Mitochondrial Genome Maintenance Exonuclease 1 (MGME1) (AA 81-260) antibody
MGME1 Reactivity: Human ELISA, WB, IHC Host: Rabbit Polyclonal unconjugated
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
Preservative
- ProClin
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Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C,-80 °C
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Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- C20orf72 (MGME1) (Mitochondrial Genome Maintenance Exonuclease 1 (MGME1))
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Alternative Name
- MGME1
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Background
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Background: Metal-dependent single-stranded DNA (ssDNA) exonuclease involved in mitochondrial genome maintenance. Has preference for 5\'-3\' exonuclease activity but is also capable of endoduclease activity on linear substrates. Necessary for maintenance of proper 7S DNA levels. Probably involved in mitochondrial DNA (mtDNA) repair, possibly via the processing of displaced DNA containing Okazaki fragments during RNA-primed DNA synthesis on the lagging strand or via processing of DNA flaps during long-patch base excision repair. Specifically binds 5-hydroxymethylcytosine (5hmC)-containing DNA in stem cells.
Aliases: MGME1 antibody, C20orf72 antibody, DDK1Mitochondrial genome maintenance exonuclease 1 antibody, EC 3.1.-.- antibody
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UniProt
- Q9BQP7
Target
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