LETM1 antibody (AA 443-543)

Catalog No. ABIN7159933

This anti-LETM1 antibody is a Rabbit Polyclonal antibody detecting LETM1 in WB, ELISA, IHC and IF. Suitable for Human.

Quick Overview for LETM1 antibody (AA 443-543) (ABIN7159933)

Target: LETM1 (Leucine Zipper-EF-Hand Containing Transmembrane Protein 1 (LETM1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LETM1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-LETM1 Antibody

Binding Specificity: AA 443-543

Cross-Reactivity: Human, Mouse

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Mitochondrial proton/calcium exchanger protein (443-543AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:500-1:5000, IHC:1:200-1:500, IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for LETM1

Target: LETM1 (Leucine Zipper-EF-Hand Containing Transmembrane Protein 1 (LETM1))

Alternative Name: LETM1

Background:

Background: Mitochondrial proton/calcium antiporter that mediates proton-dependent calcium efflux from mitochondrion (PubMed:19797662). Crucial for the maintenance of mitochondrial tubular networks and for the assembly of the supercomplexes of the respiratory chain (PubMed:18628306). Required for the maintenance of the tubular shape and cristae organization (PubMed:18628306). In contrast to SLC8B1/NCLX, does not constitute the major factor for mitochondrial calcium extrusion (PubMed:24898248).

Aliases: LETM 1 antibody, LETM1 and EF hand domain containing protein 1, mitochondrial antibody, LETM1 and EF-hand domain-containing protein 1 antibody, Letm1 antibody, LETM1_HUMAN antibody, Leucine zipper EF hand containing transmembrane protein 1 antibody, Leucine zipper-EF-hand-containing transmembrane protein 1 antibody, Mdm38 homolog antibody, mitochondrial antibody

UniProt: O95202