MPZL1 antibody (AA 195-258) (Biotin)

Catalog No. ABIN7160422

This anti-MPZL1 antibody is a Rabbit Polyclonal antibody detecting MPZL1 in ELISA. Suitable for Human.

Quick Overview for MPZL1 antibody (AA 195-258) (Biotin) (ABIN7160422)

Target: MPZL1 (Myelin Protein Zero-Like 1 (MPZL1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MPZL1 antibody is conjugated to Biotin

Application: ELISA

Product Details anti-MPZL1 Antibody (Biotin)

Binding Specificity: AA 195-258

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Myelin protein zero-like protein 1 protein (195-258AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for MPZL1

Target: MPZL1 (Myelin Protein Zero-Like 1 (MPZL1))

Alternative Name: MPZL1

Background:

Background: Cell surface receptor, which is involved in signal transduction processes. Recruits PTPN11/SHP-2 to the cell membrane and is a putative substrate of PTPN11/SHP-2. Is a major receptor for concanavalin-A (ConA) and is involved in cellular signaling induced by ConA, which probably includes Src family tyrosine-protein kinases. Isoform 3 seems to have a dominant negative role, it blocks tyrosine phosphorylation of MPZL1 induced by ConA. Isoform 1, but not isoform 2 and isoform 3, may be involved in regulation of integrin-mediated cell motility.

Aliases: MPZL1 antibody, PZR antibody, UNQ849/PRO1787 antibody, Myelin protein zero-like protein 1 antibody, Protein zero-related antibody

UniProt: O95297