CD33 antibody (AA 18-259) (Biotin)

Catalog No. ABIN7160467

This anti-CD33 antibody is a Rabbit Polyclonal antibody detecting CD33 in ELISA. Suitable for Human.

Quick Overview for CD33 antibody (AA 18-259) (Biotin) (ABIN7160467)

Target: CD33

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CD33 antibody is conjugated to Biotin

Application: ELISA

Product Details anti-CD33 Antibody (Biotin)

Binding Specificity: AA 18-259

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Myeloid cell surface antigen CD33 protein (18-259AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for CD33

Target: CD33

Alternative Name: CD33

Background:

Background: Putative adhesion molecule of myelomonocytic-derived cells that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules. Induces apoptosis in acute myeloid leukemia (in vitro).

Aliases: CD 33 antibody, CD33 antibody, CD33 antigen (gp67) antibody, CD33 antigen antibody, CD33 Molecule antibody, CD33_HUMAN antibody, FLJ00391 antibody, gp67 antibody, My9 antibody, Myeloid cell surface antigen CD33 antibody, Myeloid cell surface antigen CD33 precursor antibody, Myeloid differentiation antigen CD33 antibody, p67 antibody, Sialic acid binding Ig like lectin 3 antibody, Sialic acid binding immunoglobulin like lectin 3 antibody, Sialic acid-binding Ig-like lectin 3 antibody, SIGLEC 3 antibody, Siglec-3 antibody, SIGLEC3 antibody

UniProt: P20138