YES1 antibody (pTyr537) (HRP)

Catalog No. ABIN711860

The Rabbit Polyclonal anti-YES1 antibody is suitable to detect YES1 in samples from Human. It has been validated for WB, ELISA, IHC (p) and IHC (fro).

Quick Overview for YES1 antibody (pTyr537) (HRP) (ABIN711860)

Target: YES1 (V-Yes-1 Yamaguchi Sarcoma Viral Oncogene Homolog 1 (YES1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This YES1 antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-YES1 Antibody (HRP)

Binding Specificity: pTyr537

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Pig,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated Synthesised phosphopeptide derived from human YES1 around the phosphorylation site of Tyr537:PQ(p-Y)QP?

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for YES1

Target: YES1 (V-Yes-1 Yamaguchi Sarcoma Viral Oncogene Homolog 1 (YES1))

Alternative Name: YES1

Background:

Synonyms: YES1phospho Y537, c Yes, c-Yes, Cellular Yes 1 protein, Cellular Yes1 protein, HsT441, P61 YES, p61-Yes, Proto oncogene tyrosine protein kinase YES, Proto-oncogene c-Yes, Proto-oncogene tyrosine-protein kinase Yes, v yes 1 Yamaguchi sarcoma viral oncogene homolog 1, Viral oncogene yes 1 homolog 1, Viral oncogene yes1 homolog 1, Yamaguchi sarcoma oncogene, Yes 1, Yes, YES_HUMAN, YES1.

Background: This gene is the cellular homolog of the Yamaguchi sarcoma virus oncogene. The encoded protein has tyrosine kinase activity and belongs to the src family of proteins. This gene lies in close proximity to thymidylate synthase gene on chromosome 18, and a corresponding pseudogene has been found on chromosome 22. [provided by RefSeq].

Gene ID: 10413

UniProt: P07947

Pathways: CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Thromboxane A2 Receptor Signaling