NDN antibody (AA 1-98) (FITC)
Quick Overview for NDN antibody (AA 1-98) (FITC) (ABIN7161107)
Target
See all NDN AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 1-98
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Cross-Reactivity
- Human
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Purification
- >95%, Protein G purified
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Immunogen
- Recombinant Human Necdin protein (1-98AA)
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Isotype
- IgG
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
Preservative
- ProClin
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Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C,-80 °C
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Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- NDN (Necdin Homolog (Mouse) (NDN))
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Alternative Name
- NDN
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Background
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Background: Growth suppressor that facilitates the entry of the cell into cell cycle arrest. Functionally similar to the retinoblastoma protein it binds to and represses the activity of cell-cycle-promoting proteins such as SV40 large T antigen, adenovirus E1A, and the transcription factor E2F. Necdin also interacts with p53 and works in an additive manner to inhibit cell growth. Functions also as transcription factor and binds directly to specific guanosine-rich DNA sequences (By similarity).
Aliases: HsT16328 antibody, NDN antibody, NECD_HUMAN antibody, Necdin antibody, Necdin homolog antibody, Necdin MAGE family member antibody, necdin related protein antibody, PWCR antibody
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UniProt
- Q99608
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Pathways
- Neurotrophin Signaling Pathway
Target
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