NPHP3 antibody (AA 1-130)

Catalog No. ABIN7161157

This anti-NPHP3 antibody is a Rabbit Polyclonal antibody detecting NPHP3 in ELISA and IHC. Suitable for Human.

Quick Overview for NPHP3 antibody (AA 1-130) (ABIN7161157)

Target: NPHP3 (Nephronophthisis 3 (Adolescent) (NPHP3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NPHP3 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Product Details anti-NPHP3 Antibody

Binding Specificity: AA 1-130

Cross-Reactivity: Human

Purification: Antigen Affinity Purified

Immunogen: Recombinant Human Nephrocystin-3 protein (1-130AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for NPHP3

Target: NPHP3 (Nephronophthisis 3 (Adolescent) (NPHP3))

Alternative Name: NPHP3

Background:

Background: Required for normal ciliary development and function. Inhibits disheveled-1-induced canonical Wnt-signaling activity and may also play a role in the control of non-canonical Wnt signaling which regulates planar cell polarity. Probably acts as a molecular switch between different Wnt signaling pathways. Required for proper convergent extension cell movements.

Aliases: Meckel syndrome, type 7 antibody, MKS7 antibody, Nephrocystin-3 antibody, nephronophthisis 3 (adolescent) antibody, NPH3 antibody, Nphp3 antibody, NPHP3_HUMAN antibody, pcy antibody, RHPD antibody

UniProt: Q7Z494

Pathways: cAMP Metabolic Process