NPHP3 antibody (N-Term)

Catalog No. ABIN656679

The Rabbit Polyclonal anti-NPHP3 antibody (Clone RB32452) (ABIN656679) specifically detects NPHP3 in WB and IHC (p). The antibody is reactive with Human samples.

Quick Overview for NPHP3 antibody (N-Term) (ABIN656679)

Target: NPHP3 (Nephronophthisis 3 (Adolescent) (NPHP3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NPHP3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB32452

Product Details anti-NPHP3 Antibody

Binding Specificity: AA 144-173, N-Term

Predicted Reactivity: Zf, X

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This NPHP3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 144-173 amino acids from the N-terminal region of human NPHP3.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: NPHP3 Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

Expiry Date: 6 months

Target Details for NPHP3

Target: NPHP3 (Nephronophthisis 3 (Adolescent) (NPHP3))

Alternative Name: NPHP3

Background: This gene encodes a protein containing a coiled-coil (CC) domain, a tubulin-tyrosine ligase (TTL) domain, and a tetratrico peptide repeat (TPR) domain. The encoded protein interacts with nephrocystin and may function in renal tubular development and function. Mutations in this gene are associated with nephronophthisis type 3. Multiple splice variants have been described but their full-length nature has not been determined.

Molecular Weight: 150864

Gene ID: 27031

NCBI Accession: NP_694972

UniProt: Q7Z494

Pathways: cAMP Metabolic Process