CHRNA1 antibody (AA 25-240)

Catalog No. ABIN7161343

This anti-CHRNA1 antibody is a Rabbit Polyclonal antibody detecting CHRNA1 in ELISA, WB and IHC. Suitable for Human.

Quick Overview for CHRNA1 antibody (AA 25-240) (ABIN7161343)

Target: CHRNA1 (Acetylcholine Receptor Subunit alpha (CHRNA1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CHRNA1 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-CHRNA1 Antibody

Binding Specificity: AA 25-240

Cross-Reactivity: Human

Purification: Antigen Affinity Purified

Immunogen: Recombinant Human Neuronal acetylcholine receptor subunit alpha-10 protein (25-240AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for CHRNA1

Target: CHRNA1 (Acetylcholine Receptor Subunit alpha (CHRNA1))

Alternative Name: CHRNA1

Background:

Background: Ionotropic receptor with a probable role in the modulation of auditory stimuli. Agonist binding may induce an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. The channel is permeable to a range of divalent cations including calcium, the influx of which may activate a potassium current which hyperpolarizes the cell membrane. In the ear, this may lead to a reduction in basilar membrane motion, altering the activity of auditory nerve fibers and reducing the range of dynamic hearing. This may protect against acoustic trauma.

Aliases: Acetylcholine receptor, neuronal nicotinic, alpha-10 subunit antibody, ACH10_HUMAN antibody, Alpha 10 nAChR antibody, Cholinergic receptor nicotinic alpha 10 antibody, Cholinergic receptor, neuronal nicotinic, alpha polypeptide 10 antibody, Cholinergic receptor, nicotinic, alpha polypeptide 10 antibody, CHRNA 10 antibody, CHRNA10 antibody, NACHR alpha 10 antibody, NACHR alpha-10 antibody, NACHRA10 antibody, Neuronal acetylcholine receptor protein subunit alpha 10 antibody, Neuronal acetylcholine receptor subunit alpha-10 antibody, Nicotinic acetylcholine receptor subunit alpha 10 antibody, Nicotinic acetylcholine receptor subunit alpha-10 antibody, OTTHUMP00000013620 antibody

UniProt: Q9GZZ6

Pathways: Skeletal Muscle Fiber Development