NCOA6 antibody (AA 285-504)

Catalog No. ABIN7161865

This anti-NCOA6 antibody is a Rabbit Polyclonal antibody detecting NCOA6 in ELISA and IHC. Suitable for Human.

Quick Overview for NCOA6 antibody (AA 285-504) (ABIN7161865)

Target: NCOA6 (Nuclear Receptor Coactivator 6 (NCOA6))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NCOA6 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Product Details anti-NCOA6 Antibody

Binding Specificity: AA 285-504

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Nuclear receptor coactivator 6 protein (285-504AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for NCOA6

Target: NCOA6 (Nuclear Receptor Coactivator 6 (NCOA6))

Alternative Name: NCOA6

Background:

Background: Nuclear receptor coactivator that directly binds nuclear receptors and stimulates the transcriptional activities in a hormone-dependent fashion. Coactivates expression in an agonist- and AF2-dependent manner. Involved in the coactivation of different nuclear receptors, such as for steroids (GR and ERs), retinoids (RARs and RXRs), thyroid hormone (TRs), vitamin D3 (VDR) and prostanoids (PPARs). Probably functions as a general coactivator, rather than just a nuclear receptor coactivator. May also be involved in the coactivation of the NF-kappa-B pathway. May coactivate expression via a remodeling of chromatin and its interaction with histone acetyltransferase proteins.

Aliases: NCOA6 antibody, AIB3 antibody, KIAA0181 antibody, RAP250 antibody, TRBP antibody, Nuclear receptor coactivator 6 antibody, Activating signal cointegrator 2 antibody, ASC-2 antibody, Amplified in breast cancer protein 3 antibody, Cancer-amplified transcriptional coactivator ASC-2 antibody, Nuclear receptor coactivator RAP250 antibody, NRC RAP250 antibody, Nuclear receptor-activating protein antibody, 250 kDa antibody, Peroxisome proliferator-activated receptor-interacting protein antibody, PPAR-interacting protein antibody, PRIP antibody, Thyroid hormone receptor-binding protein antibody

UniProt: Q14686

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha