NR2E1 antibody (AA 106-385)

Catalog No. ABIN7161905

This Rabbit Polyclonal antibody specifically detects NR2E1 in WB, ELISA and IHC. It exhibits reactivity toward Human.

Quick Overview for NR2E1 antibody (AA 106-385) (ABIN7161905)

Target: NR2E1 (Nuclear Receptor Subfamily 2, Group E, Member 1 (NR2E1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NR2E1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-NR2E1 Antibody

Binding Specificity: AA 106-385

Cross-Reactivity: Human, Mouse

Purification: Antigen Affinity Purified

Immunogen: Recombinant Human Nuclear receptor subfamily 2 group E member 1 protein (106-385AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for NR2E1

Target: NR2E1 (Nuclear Receptor Subfamily 2, Group E, Member 1 (NR2E1))

Alternative Name: NR2E1

Background:

Background: Orphan receptor that binds DNA as a monomer to hormone response elements (HRE) containing an extended core motif half-site sequence 5\\\'-AAGGTCA-3\\\' in which the 5\\\' flanking nucleotides participate in determining receptor specificity (By similarity). May be required to pattern anterior brain differentiation. Involved in the regulation of retinal development and essential for vision. During retinogenesis, regulates PTEN-Cyclin D expression via binding to the promoter region of PTEN and suppressing its activity (By similarity). May be involved in retinoic acid receptor (RAR) regulation in retinal cells.

Aliases: hTll antibody, NR2E1 / Tailless antibody, nr2e1 antibody, NR2E1_HUMAN antibody, Nuclear receptor subfamily 2 group E member 1 antibody, Nuclear receptor TLX antibody, Orphan nuclear receptor NR2E1 antibody, Protein tailless homolog antibody, Tailless homolog antibody, Tll antibody, TLX antibody, XTLL antibody

UniProt: Q9Y466

Pathways: Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Stem Cell Maintenance