Oligophrenin 1 antibody (AA 1-270)

Catalog No. ABIN7162208

This Rabbit Polyclonal antibody specifically detects Oligophrenin 1 in IHC and ELISA. It exhibits reactivity toward Human.

Quick Overview for Oligophrenin 1 antibody (AA 1-270) (ABIN7162208)

Target: Oligophrenin 1 (OPHN1)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Oligophrenin 1 antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA

Product Details anti-Oligophrenin 1 Antibody

Binding Specificity: AA 1-270

Cross-Reactivity: Human

Purification: Antigen Affinity Purified

Immunogen: Recombinant Human Oligophrenin-1 protein (1-270AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for Oligophrenin 1

Target: Oligophrenin 1 (OPHN1)

Alternative Name: OPHN1

Background:

Background: Stimulates GTP hydrolysis of members of the Rho family. Its action on RHOA activity and signaling is implicated in growth and stabilization of dendritic spines, and therefore in synaptic function. Critical for the stabilization of AMPA receptors at postsynaptic sites. Critical for the regulation of synaptic vesicle endocytosis at presynaptic terminals. Required for the localization of NR1D1 to dendrites, can suppress its repressor activity and protect it from proteasomal degradation (By similarity).

Aliases: OPHN1 antibody, Oligophrenin-1 antibody

UniProt: O60890