PIK3AP1 antibody (AA 293-404) (HRP)

Catalog No. ABIN7163290

This anti-PIK3AP1 antibody is a Rabbit Polyclonal antibody detecting PIK3AP1 in ELISA. Suitable for Human.

Quick Overview for PIK3AP1 antibody (AA 293-404) (HRP) (ABIN7163290)

Target: PIK3AP1 (phosphoinositide-3-Kinase Adaptor Protein 1 (PIK3AP1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PIK3AP1 antibody is conjugated to HRP

Application: ELISA

Product Details anti-PIK3AP1 Antibody (HRP)

Binding Specificity: AA 293-404

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Phosphoinositide 3-kinase adapter protein 1 protein (293-404AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for PIK3AP1

Target: PIK3AP1 (phosphoinositide-3-Kinase Adaptor Protein 1 (PIK3AP1))

Alternative Name: PIK3AP1

Background:

Background: Signaling adapter that contributes to B-cell development by linking B-cell receptor (BCR) signaling to the phosphoinositide 3-kinase (PI3K)-Akt signaling pathway. Has a complementary role to the BCR coreceptor CD19, coupling BCR and PI3K activation by providing a docking site for the PI3K subunit PIK3R1. Alternatively, links Toll-like receptor (TLR) signaling to PI3K activation, a process preventing excessive inflammatory cytokine production. Also involved in the activation of PI3K in natural killer cells. May be involved in the survival of mature B-cells via activation of REL.

Aliases: PIK3AP1 antibody, BCAPPhosphoinositide 3-kinase adapter protein 1 antibody, B-cell adapter for phosphoinositide 3-kinase antibody, B-cell phosphoinositide 3-kinase adapter protein 1 antibody

UniProt: Q6ZUJ8

Pathways: Activation of Innate immune Response, BCR Signaling, Warburg Effect