SUZ12 antibody (AA 131-305) (HRP)

Catalog No. ABIN7163814

The Rabbit Polyclonal anti-SUZ12 antibody has been validated for ELISA. It is suitable to detect SUZ12 in samples from Human.

Quick Overview for SUZ12 antibody (AA 131-305) (HRP) (ABIN7163814)

Target: SUZ12 (SUZ12 Polycomb Repressive Complex 2 Subunit (SUZ12))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SUZ12 antibody is conjugated to HRP

Application: ELISA

Product Details anti-SUZ12 Antibody (HRP)

Binding Specificity: AA 131-305

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Polycomb protein SUZ12 protein (131-305AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for SUZ12

Target: SUZ12 (SUZ12 Polycomb Repressive Complex 2 Subunit (SUZ12))

Alternative Name: SUZ12

Background:

Background: Polycomb group (PcG) protein. Component of the PRC2/EED-EZH2 complex, which methylates \\\'Lys-9\\\' (H3K9me) and \\\'Lys-27\\\' (H3K27me) of histone H3, leading to transcriptional repression of the affected target gene. The PRC2/EED-EZH2 complex may also serve as a recruiting platform for DNA methyltransferases, thereby linking two epigenetic repression systems. Genes repressed by the PRC2/EED-EZH2 complex include HOXC8, HOXA9, MYT1 and CDKN2A.

Aliases: ChET 9 protein antibody, CHET9 antibody, Chromatin precipitated E2F target 9 protein antibody, JJAZ1 antibody, Joined to JAZF1 protein antibody, KIAA0160 antibody, Polycomb protein SUZ12 antibody, Suppressor of zeste 12 homolog antibody, Suppressor of zeste 12 protein homolog antibody, SUZ12 antibody, SUZ12 polycomb repressive complex 2 subunit antibody, SUZ12_HUMAN antibody

UniProt: Q15022