OCT4 antibody (AA 1-360)

Catalog No. ABIN7164068

This Mouse Monoclonal antibody specifically detects OCT4 in WB, ELISA, IHC, IF and FACS. It exhibits reactivity toward Human.

Quick Overview for OCT4 antibody (AA 1-360) (ABIN7164068)

Target: OCT4 (POU5F1) (POU Class 5 Homeobox 1 (POU5F1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This OCT4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)

Clone: 2H41D8

Product Details anti-OCT4 Antibody

Binding Specificity: AA 1-360

Cross-Reactivity: Human, Mouse, Rat

Purification: Protein G purified

Immunogen: Recombinant Human POU domain, class 5, transcription factor 1 protein (1-360AA)

Isotype: IgG2b

Application Details

Application Notes: Recommended dilution: WB:1:500-1:10000, IHC:1:50-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for OCT4

Target: OCT4 (POU5F1) (POU Class 5 Homeobox 1 (POU5F1))

Alternative Name: OCT4

Background:

Background: Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3'). Forms a trimeric complex with SOX2 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. Critical for early embryogenesis and for embryonic stem cell pluripotency.

Aliases: POU domain, class 5, transcription factor 1 (Octamer-binding protein 3) (Oct-3) (Octamer-binding protein 4) (Oct-4) (Octamer-binding transcription factor 3) (OTF-3), POU5F1, OCT3 OCT4 OTF3

UniProt: Q01860

Pathways: Stem Cell Maintenance