PD-1 antibody (AA 1-212) (Biotin)

Catalog No. ABIN7164688

This anti-PD-1 antibody is a Rabbit Polyclonal antibody detecting PD-1 in ELISA. Suitable for Human.

Quick Overview for PD-1 antibody (AA 1-212) (Biotin) (ABIN7164688)

Target: PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PD-1 antibody is conjugated to Biotin

Application: ELISA

Product Details anti-PD-1 Antibody (Biotin)

Binding Specificity: AA 1-212

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Programmed cell death protein 10 protein (1-212AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for PD-1

Target: PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))

Alternative Name: PDCD1

Background:

Background: Promotes cell proliferation. Modulates apoptotic pathways. Increases mitogen-activated protein kinase activity and STK26 activity. Important for cell migration, and for normal structure and assembly of the Golgi complex. Important for KDR/VEGFR2 signaling. Increases the stability of KDR/VEGFR2 and prevents its breakdown. Required for normal cardiovascular development. Required for normal angiogenesis, vasculogenesis and hematopoiesis during embryonic development (By similarity).

Aliases: Apoptosis related protein 15 antibody, CCM3 antibody, Cerebral cavernous malformations 3 protein antibody, MGC1212 antibody, MGC24477 antibody, PDC10_HUMAN antibody, PDCD 10 antibody, PDCD10 antibody, Programmed cell death 10 antibody, Programmed cell death protein 10 antibody, TF 1 cell apoptosis related protein 15 antibody, TF-1 cell apoptosis-related protein 15 antibody, TFAR15 antibody

UniProt: Q9BUL8

Pathways: Cancer Immune Checkpoints