Prohibitin 2 antibody (AA 1-299)

Catalog No. ABIN7164708

The Rabbit Polyclonal anti-Prohibitin 2 antibody has been validated for WB, IHC and ELISA. It is suitable to detect Prohibitin 2 in samples from Human.

Quick Overview for Prohibitin 2 antibody (AA 1-299) (ABIN7164708)

Target: Prohibitin 2 (PHB2)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Prohibitin 2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-Prohibitin 2 Antibody

Binding Specificity: AA 1-299

Cross-Reactivity: Human

Purification: Antigen Affinity Purified

Immunogen: Recombinant Human Prohibitin-2 protein (1-299AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for Prohibitin 2

Target: Prohibitin 2 (PHB2)

Alternative Name: PHB2

Background:

Background: Acts as a mediator of transcriptional repression by nuclear hormone receptors via recruitment of histone deacetylases (By similarity). Functions as an estrogen receptor (ER)-selective coregulator that potentiates the inhibitory activities of antiestrogens and represses the activity of estrogens. Competes with NCOA1 for modulation of ER transcriptional activity. Probably involved in regulating mitochondrial respiration activity and in aging.

Aliases: B cell receptor associated protein BAP37 antibody, B-cell receptor-associated protein BAP37 antibody, BAP antibody, Bap37 antibody, BCAP 37 antibody, D prohibitin antibody, D-prohibitin antibody, p22 antibody, Phb2 antibody, PHB2_HUMAN antibody, PNAS 141 antibody, Prohibitin 2 antibody, Prohibitin-2 antibody, Repressor of estrogen receptor activity antibody

UniProt: Q99623

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling