PA2G4 antibody (AA 2-394) (HRP)

Catalog No. ABIN7164749

This Rabbit Polyclonal antibody specifically detects PA2G4 in ELISA. It exhibits reactivity toward Human.

Quick Overview for PA2G4 antibody (AA 2-394) (HRP) (ABIN7164749)

Target: PA2G4 (Proliferation-Associated 2G4, 38kDa (PA2G4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PA2G4 antibody is conjugated to HRP

Application: ELISA

Product Details anti-PA2G4 Antibody (HRP)

Binding Specificity: AA 2-394

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Proliferation-associated protein 2G4 protein (2-394AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for PA2G4

Target: PA2G4 (Proliferation-Associated 2G4, 38kDa (PA2G4))

Alternative Name: PA2G4

Background:

Background: May play a role in a ERBB3-regulated signal transduction pathway. Seems be involved in growth regulation. Acts a corepressor of the androgen receptor (AR) and is regulated by the ERBB3 ligand neuregulin-1/heregulin (HRG). Inhibits transcription of some E2F1-regulated promoters, probably by recruiting histone acetylase (HAT) activity. Binds RNA. Associates with 28S, 18S and 5.8S mature rRNAs, several rRNA precursors and probably U3 small nucleolar RNA. May be involved in regulation of intermediate and late steps of rRNA processing. May be involved in ribosome assembly. Mediates cap-independent translation of specific viral IRESs (internal ribosomal entry site) (By similarity). Regulates cell proliferation, differentiation, and survival. Isoform 1 suppresses apoptosis whereas isoform 2 promotes cell differentiation (By similarity).

Aliases: 38 kDa antibody, AA672939 antibody, Cell cycle protein p38 2G4 homolog antibody, Cell cycle protein p38-2G4 homolog antibody, ErbB-3 binding protein 1 antibody, ErbB3 binding protein 1 antibody, ErbB3-binding protein 1 antibody, ErbB3-binding protein Ebp1 antibody, hG4 1 antibody, hG4-1 antibody, IRES-specific cellular trans-acting factor 45 kDa antibody, MGC81621 antibody, MGC94070 antibody, Mpp1 antibody, p38 2G4 antibody, Pa2g4 antibody, PA2G4_HUMAN antibody, Plfap antibody, Proliferation associated 2G4 antibody, Proliferation associated 2G4, 38-KD antibody, Proliferation-associated 2G4, 38 kDa antibody, Proliferation-associated 2G4, a antibody, Proliferation-associated protein 1 antibody, Proliferation-associated protein 2G4 antibody, Protein p38-2G4 antibody, si:dz150i12.2 antibody, wu:fb19b11 antibody, wu:ft56d05 antibody, zgc:86732 antibody

UniProt: Q9UQ80

Pathways: Myometrial Relaxation and Contraction, Regulation of Carbohydrate Metabolic Process, Hepatitis C, Toll-Like Receptors Cascades