PROX1 antibody (AA 262-477)
Quick Overview for PROX1 antibody (AA 262-477) (ABIN7164844)
Target
See all PROX1 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 262-477
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Cross-Reactivity
- Human
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Purification
- >95%, Protein G purified
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Immunogen
- Recombinant Human Prospero homeobox protein 1 protein (262-477AA)
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Isotype
- IgG
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Application Notes
- Recommended dilution: WB:1:500-1:5000,
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
Preservative
- ProClin
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Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C,-80 °C
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Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- PROX1 (Prospero Homeobox 1 (PROX1))
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Alternative Name
- PROX1
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Background
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Background: Transcription factor involved in developmental processes such as cell fate determination, gene transcriptional regulation and progenitor cell regulation in a number of organs. Plays a critical role in embryonic development and functions as a key regulatory protein in neurogenesis and the development of the heart, eye lens, liver, pancreas and the lymphatic system. Involved in the regulation of the circadian rhythm. Represses: transcription of the retinoid-related orphan receptor RORG, transcriptional activator activity of RORA and RORG and the expression of RORA/G-target genes including core clock components: ARNTL/BMAL1, NPAS2 and CRY1 and metabolic genes: AVPR1A and ELOVL3.
Aliases: Homeobox prospero like protein antibody, Homeobox prospero like protein PROX1 antibody, Homeobox prospero-like protein PROX1 antibody, Prospero homeobox 1 antibody, Prospero homeobox protein 1 antibody, Prospero related homeobox 1 antibody, prospero-related homeobox gene 1 antibody, PROX 1 antibody, PROX-1 antibody, PROX1 antibody, PROX1_HUMAN antibody, zgc:111888 antibody
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UniProt
- Q92786
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Pathways
- Stem Cell Maintenance, Regulation of Muscle Cell Differentiation
Target
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