PSMB2 antibody (AA 1-201)

Catalog No. ABIN7164973

The Rabbit Polyclonal anti-PSMB2 antibody (ABIN7164973) specifically detects PSMB2 in WB, ELISA, IHC and IF. The antibody is reactive with Human samples.

Quick Overview for PSMB2 antibody (AA 1-201) (ABIN7164973)

Target: PSMB2 (Proteasome (Prosome, Macropain) Subunit, beta Type 2 (PSMB2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PSMB2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-PSMB2 Antibody

Binding Specificity: AA 1-201

Purpose: PSMB2 Antibody

Cross-Reactivity: Mouse

Purification: Protein G purified

Purity: >95 %

Immunogen: Recombinant Human Proteasome subunit beta type-2 protein (1-201AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for PSMB2

Target: PSMB2 (Proteasome (Prosome, Macropain) Subunit, beta Type 2 (PSMB2))

Alternative Name: PSMB2

Background:

Background: The proteasome is a multicatalytic proteinase complex with a highly ordered ring shaped 20S core structure. The core structure is composed of 4 rings of 28 non identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. PSMB2 is a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit.The proteasome is a multicatalytic proteinase complex with a highly ordered ring shaped 20S core structure. The core structure is composed of 4 rings of 28 non identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin dependent process in a non lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B type family, also known as the T1B family, that is a 20S core beta subunit. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Aliases: HC7 I antibody, Macropain subunit C7 I antibody, Macropain subunit C7-I antibody, Multicatalytic endopeptidase complex subunit C7 1 antibody, Multicatalytic endopeptidase complex subunit C7 I antibody, Multicatalytic endopeptidase complex subunit C7-I antibody, Proteasome (prosome, macropain) subunit beta type 2 antibody, Proteasome beta 2 subunit antibody, Proteasome component C7 I antibody, Proteasome component C7-I antibody, Proteasome subunit beta type-2 antibody, PSB2_HUMAN antibody, Psmb2 antibody

UniProt: P49721

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA