IMPACT antibody (AA 41-320) (HRP)

Catalog No. ABIN7165648

This anti-IMPACT antibody is a Rabbit Polyclonal antibody detecting IMPACT in ELISA. Suitable for Human.

Quick Overview for IMPACT antibody (AA 41-320) (HRP) (ABIN7165648)

Target: IMPACT (Impact Homolog (IMPACT))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IMPACT antibody is conjugated to HRP

Application: ELISA

Product Details anti-IMPACT Antibody (HRP)

Binding Specificity: AA 41-320

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Protein IMPACT protein (41-320AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for IMPACT

Target: IMPACT (Impact Homolog (IMPACT))

Alternative Name: IMPACT

Background:

Background: Translational regulator that ensures constant high levels of translation under amino acid starvation. Acts by interacting with GCN1/GCN1L1, thereby preventing activation of GCN2 protein kinases (EIF2AK1 to 4) and subsequent down-regulation of protein synthesis. May be required to regulate translation in specific neuronal cells under amino acid starvation conditions by preventing GCN2 activation and therefore ATF4 synthesis. Through its action on GCN2, may also facilitate neuritogenesis.

Aliases: IMPACT antibody, Impact homolog (mouse) antibody, Impact homolog antibody, impact RWD domain protein antibody, IMPCT_HUMAN antibody, Imprinted and ancient gene protein homolog antibody, MGC33718 antibody, Protein IMPACT antibody, RWD domain containing 5 antibody, RWDD5 antibody

UniProt: Q9P2X3