INTU antibody (AA 6-139)

Catalog No. ABIN7165653

The Rabbit Polyclonal anti-INTU antibody has been validated for ELISA, IF and IHC. It is suitable to detect INTU in samples from Human.

Quick Overview for INTU antibody (AA 6-139) (ABIN7165653)

Target: INTU (Inturned Planar Cell Polarity Effector Homolog (INTU))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This INTU antibody is un-conjugated

Application: ELISA, Immunofluorescence (IF), Immunohistochemistry (IHC)

Product Details anti-INTU Antibody

Binding Specificity: AA 6-139

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Protein inturned protein (6-139AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:200-1:500, IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for INTU

Target: INTU (Inturned Planar Cell Polarity Effector Homolog (INTU))

Alternative Name: INTU

Background:

Background: Plays a key role in ciliogenesis and embryonic development. Regulator of cilia formation by controlling the organization of the apical actin cytoskeleton and the positioning of the basal bodies at the apical cell surface, which in turn is essential for the normal orientation of elongating ciliary microtubules. Plays a key role in definition of cell polarity via its role in ciliogenesis but not via conversion extension. Has an indirect effect on hedgehog signaling (By similarity). Proposed to function as core component of the CPLANE (ciliogenesis and planar polarity effectors) complex involved in the recruitment of peripheral IFT-A proteins to basal bodies (PubMed:27158779).

Aliases: Homolog of inturned (X. tropicalis) antibody, INT antibody, intu antibody, Inturned planar cell polarity effector homolog antibody, KIAA1284 antibody, PDZ domain containing 6 antibody, PDZ domain-containing protein 6 antibody, PDZD 6 antibody, PDZD6_HUMAN antibody, PDZK6 antibody

UniProt: Q9ULD6