PCMT1 antibody (AA 117-228) (Biotin)

Catalog No. ABIN7166421

The Rabbit Polyclonal anti-PCMT1 antibody has been validated for ELISA. It is suitable to detect PCMT1 in samples from Human.

Quick Overview for PCMT1 antibody (AA 117-228) (Biotin) (ABIN7166421)

Target: PCMT1 (Protein-L-Isoaspartate (D-Aspartate) O-Methyltransferase (PCMT1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PCMT1 antibody is conjugated to Biotin

Application: ELISA

Product Details anti-PCMT1 Antibody (Biotin)

Binding Specificity: AA 117-228

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Protein-L-isoaspartate(D-aspartate) O-methyltransferase protein (117-228AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for PCMT1

Target: PCMT1 (Protein-L-Isoaspartate (D-Aspartate) O-Methyltransferase (PCMT1))

Alternative Name: PCMT1

Background:

Background: Catalyzes the methyl esterification of L-isoaspartyl and D-aspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins. Acts on EIF4EBP2, microtubule-associated protein 2, calreticulin, clathrin light chains a and b, Ubiquitin carboxyl-terminal hydrolase isozyme L1, phosphatidylethanolamine-binding protein 1, stathmin, beta-synuclein and alpha-synuclein.

Aliases: PCMT1 antibody, Protein-L-isoaspartate(D-aspartate) O-methyltransferase antibody, PIMT antibody, EC 2.1.1.77 antibody, L-isoaspartyl protein carboxyl methyltransferase antibody, Protein L-isoaspartyl/D-aspartyl methyltransferase antibody, Protein-beta-aspartate methyltransferase antibody

UniProt: P22061

Pathways: Ribonucleoprotein Complex Subunit Organization