TDRD12 antibody (AA 991-1164)
Quick Overview for TDRD12 antibody (AA 991-1164) (ABIN7166667)
Target
Reactivity
Host
Clonality
Conjugate
Application
-
-
Binding Specificity
- AA 991-1164
-
Cross-Reactivity
- Human
-
Purification
- >95%, Protein G purified
-
Immunogen
- Recombinant Human Putative ATP-dependent RNA helicase TDRD12 protein (991-1164AA)
-
Isotype
- IgG
-
-
anti-Tudor Domain Containing 12 (TDRD12) (C-Term) antibody
TDRD12 Reactivity: Human, Cow, Horse, Pig WB Host: Rabbit Polyclonal unconjugated
-
-
Application Notes
- Recommended dilution: IHC:1:20-1:200,
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Buffer
-
Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
Preservative
- ProClin
-
Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Storage
- -20 °C,-80 °C
-
Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
-
-
- TDRD12 (Tudor Domain Containing 12 (TDRD12))
-
Alternative Name
- TDRD12
-
Background
-
Background: Probable ATP-binding RNA helicase required during spermatogenesis to repress transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Involved in the secondary piRNAs metabolic process. Acts via the PET complex, a multiprotein complex required during the secondary piRNAs metabolic process for the PIWIL2 slicing-triggered loading of PIWIL4 piRNAs.
Aliases: ECAT8 antibody, ES cell associated transcript 8 antibody, ES cell-associated transcript 8 protein antibody, TDR12_HUMAN antibody, Tdrd12 antibody, Tudor domain containing 12 antibody, Tudor domain-containing protein 12 antibody
-
UniProt
- Q587J7
Target
-
