RALBP1 antibody (AA 6-105)

Catalog No. ABIN7167078

The Rabbit Polyclonal anti-RALBP1 antibody has been validated for WB, IHC, ELISA and IF. It is suitable to detect RALBP1 in samples from Human.

Quick Overview for RALBP1 antibody (AA 6-105) (ABIN7167078)

Target: RALBP1 (RalA Binding Protein 1 (RALBP1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RALBP1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Product Details anti-RALBP1 Antibody

Binding Specificity: AA 6-105

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human RalA-binding protein 1 protein (6-105AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for RALBP1

Target: RALBP1 (RalA Binding Protein 1 (RALBP1))

Alternative Name: RALBP1

Background:

Background: Can activate specifically hydrolysis of GTP bound to RAC1 and CDC42, but not RALA. Mediates ATP-dependent transport of S-(2,4-dinitrophenyl)-glutathione (DNP-SG) and doxorubicin (DOX) and is the major ATP-dependent transporter of glutathione conjugates of electrophiles (GS-E) and DOX in erythrocytes. Can catalyze transport of glutathione conjugates and xenobiotics, and may contribute to the multidrug resistance phenomenon. Serves as a scaffold protein that brings together proteins forming an endocytotic complex during interphase and also with CDK1 to switch off endocytosis, One of its substrates would be EPN1/Epsin.

Aliases: RLIP1 antibody, 76 kDa Ral-interacting protein antibody, 76- kDa Ral-interacting protein antibody, Dinitrophenyl S-glutathione ATPase antibody, DNP-SG ATPase antibody, Ral-interacting protein 1 antibody, Ral-interacting protein 1, 76-KD antibody, RalA-binding protein 1 antibody, RalBP1 antibody, RBP1_HUMAN antibody, RIP1 antibody, RLIP1 antibody, RLIP76 antibody

UniProt: Q15311