RAB23 antibody (AA 1-237)

Catalog No. ABIN7167252

The Rabbit Polyclonal anti-RAB23 antibody has been validated for WB, ELISA and IHC. It is suitable to detect RAB23 in samples from Human.

Quick Overview for RAB23 antibody (AA 1-237) (ABIN7167252)

Target: RAB23 (RAB23, Member RAS Oncogene Family (RAB23))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RAB23 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-RAB23 Antibody

Binding Specificity: AA 1-237

Cross-Reactivity: Human, Mouse, Rat

Purification: Antigen Affinity Purified

Immunogen: Recombinant Human Ras-related protein Rab-23 protein (1-237AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for RAB23

Target: RAB23 (RAB23, Member RAS Oncogene Family (RAB23))

Alternative Name: RAB23

Background:

Background: The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. Together with SUFU, prevents nuclear import of GLI1, and thereby inhibits GLI1 transcription factor activity. Regulates GLI1 in differentiating chondrocytes. Likewise, regulates GLI3 proteolytic processing and modulates GLI2 and GLI3 transcription factor activity. Plays a role in autophagic vacuole assembly, and mediates defense against pathogens, such as S.aureus, by promoting their capture by autophagosomes that then merge with lysosomes.

Aliases: DKFZp781H0695 antibody, HSPC137 antibody, MGC8900 antibody, Rab 23 antibody, RAB family small GTP binding protein RAB 23 antibody, Rab23 antibody, RAB23, member RAS oncogene family antibody, RAB23_HUMAN antibody, Ras related protein Rab 23 antibody, Ras-related protein Rab-23 antibody

UniProt: Q9ULC3

Pathways: Tube Formation