RAB35 antibody (AA 1-201)

Catalog No. ABIN7167302

This Rabbit Polyclonal antibody specifically detects RAB35 in ELISA, IHC and IF. It exhibits reactivity toward Human.

Quick Overview for RAB35 antibody (AA 1-201) (ABIN7167302)

Target: RAB35 (RAB35, Member RAS Oncogene Family (RAB35))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RAB35 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-RAB35 Antibody

Binding Specificity: AA 1-201

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Ras-related protein Rab-35 protein (1-201AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:200-1:500, IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for RAB35

Target: RAB35 (RAB35, Member RAS Oncogene Family (RAB35))

Alternative Name: RAB35

Background:

Background: The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. That Rab is involved in the process of endocytosis and is an essential rate-limiting regulator of the fast recycling pathway back to the plasma membrane. During cytokinesis, required for the postfurrowing terminal steps, namely for intercellular bridge stability and abscission, possibly by controlling phosphatidylinositol 4,5-bis phosphate (PIP2) and SEPT2 localization at the intercellular bridge. May indirectly regulate neurite outgrowth. Together with TBC1D13 may be involved in regulation of insulin-induced glucose transporter SLC2A4/GLUT4 translocation to the plasma membrane in adipocytes.

Aliases: GTP binding protein RAY antibody, GTP-binding protein RAY antibody, H ray antibody, OTTHUMP00000240256 antibody, OTTHUMP00000240257 antibody, OTTHUMP00000240258 antibody, OTTHUMP00000240259 antibody, RAB1C antibody, Rab35 antibody, RAB35 member RAS oncogene family antibody, RAB35, member RAS oncogene family antibody, RAB35_HUMAN antibody, Ras related protein rab 1c (GTP binding protein ray) antibody, Ras related protein Rab 1C antibody, Ras related protein Rab35 antibody, Ras-related protein Rab-1C antibody, Ras-related protein Rab-35 antibody, RAY antibody

UniProt: Q15286