RNLS antibody (AA 18-342)
Quick Overview for RNLS antibody (AA 18-342) (ABIN7167670)
Target
See all RNLS AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 18-342
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Cross-Reactivity
- Human
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Purification
- Antigen Affinity Purified
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Immunogen
- Recombinant Human Renalase protein (18-342AA)
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Isotype
- IgG
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Application Notes
- Recommended dilution: IHC:1:20-1:200,
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C,-80 °C
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Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- RNLS (Renalase, FAD-Dependent Amine Oxidase (RNLS))
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Alternative Name
- RNLS
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Background
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Background: Catalyzes the oxidation of the less abundant alpha-NAD(P)H isoform to form beta-NAD(P)+. The enzyme hormone is secreted by the kidney, and circulates in blood and modulates cardiac function and systemic blood pressure. Lowers blood pressure in vivo by decreasing cardiac contractility and heart rate and preventing a compensatory increase in peripheral vascular tone, suggesting a causal link to the increased plasma catecholamine and heightened cardiovascular risk. High concentrations of catecholamines activate plasma renalase and promotes its secretion and synthesis.
Aliases: 6530404N21Rik antibody, AI452315 antibody, AW060440 antibody, C10orf59 antibody, Chromosome 10 open reading frame 59 antibody, FLJ11218 antibody, HGNC:25641 antibody, Hypothetical protein LOC55328 antibody, MAO C antibody, MAO-C antibody, mMAO C antibody, Monoamine oxidase C antibody, Monoamine oxidase-C antibody, Renalase antibody, Renalase FAD dependent amine oxidase antibody, RNLS antibody, RNLS_HUMAN antibody
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UniProt
- Q5VYX0
Target
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