ARHGEF11 antibody (AA 1221-1318) (Biotin)

Catalog No. ABIN7167965

Product Details anti-ARHGEF11 Antibody (Biotin)

Target: ARHGEF11 (rho Guanine Nucleotide Exchange Factor (GEF) 11 (ARHGEF11))

Binding Specificity: AA 1221-1318

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ARHGEF11 antibody is conjugated to Biotin

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Rho guanine nucleotide exchange factor 11 protein (1221-1318AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for ARHGEF11

Target: ARHGEF11 (rho Guanine Nucleotide Exchange Factor (GEF) 11 (ARHGEF11))

Alternative Name: ARHGEF11 (ARHGEF11 Products)

Synonyms: ARHGEF11 antibody, GTRAP48 antibody, PDZ-RHOGEF antibody, B930073M02 antibody, E130307F09 antibody, PDZ-RhoGEF antibody, Prg antibody, RhoGEF antibody, mKIAA0380 antibody, Gtrap48 antibody, Rho guanine nucleotide exchange factor (GEF) 11 antibody, Rho guanine nucleotide exchange factor 11 antibody, rho guanine nucleotide exchange factor 11 antibody, arhgef11 antibody, ARHGEF11 antibody, Arhgef11 antibody, LOC511220 antibody

Background:

Background: May play a role in the regulation of RhoA GTPase by guanine nucleotide-binding alpha-12 (GNA12) and alpha-13 (GNA13). Acts as guanine nucleotide exchange factor (GEF) for RhoA GTPase and may act as GTPase-activating protein (GAP) for GNA12 and GNA13. Involved in neurotrophin-induced neurite outgrowth.

Aliases: ARHGB_HUMAN antibody, ARHGEF 11 antibody, ARHGEF11 antibody, DKFZp667F1223 antibody, Glutamate transporter EAAT4 associated protein 48 antibody, GTRAP 48 antibody, GTRAP48 antibody, KIAA0380 antibody, OTTHUMP00000038716 antibody, OTTHUMP00000038717 antibody, PDZ RHOGEF antibody, PDZ-RhoGEF antibody, Rho guanine exchange factor (GEF) 11 antibody, Rho guanine nucleotide exchange factor (GEF) 11 antibody, Rho guanine nucleotide exchange factor 11 antibody, RhoA specific guanine nucleotide exchange factor antibody, RhoGEF glutamate transport modulator antibody

UniProt: O15085

Pathways: Neurotrophin Signaling Pathway, Regulation of G-Protein Coupled Receptor Protein Signaling