ARHGEF7 antibody (AA 1-250)

Catalog No. ABIN7167994

This anti-ARHGEF7 antibody is a Rabbit Polyclonal antibody detecting ARHGEF7 in ELISA, IP and IF. Suitable for Human.

Quick Overview for ARHGEF7 antibody (AA 1-250) (ABIN7167994)

Target: ARHGEF7 (rho Guanine Nucleotide Exchange Factor (GEF) 7 (ARHGEF7))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ARHGEF7 antibody is un-conjugated

Application: ELISA, Immunoprecipitation (IP), Immunofluorescence (IF)

Product Details anti-ARHGEF7 Antibody

Binding Specificity: AA 1-250

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Rho guanine nucleotide exchange factor 7 protein (1-250AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IF:1:200-1:500, IP:1:200-1:2000,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for ARHGEF7

Target: ARHGEF7 (rho Guanine Nucleotide Exchange Factor (GEF) 7 (ARHGEF7))

Alternative Name: ARHGEF7

Background:

Background: Acts as a RAC1 guanine nucleotide exchange factor (GEF) and can induce membrane ruffling. Functions in cell migration, attachment and cell spreading. Promotes targeting of RAC1 to focal adhesions By similarity. May function as a positive regulator of apoptosis. Downstream of NMDA receptors and CaMKK-CaMK1 signaling cascade, promotes the formation of spines and synapses in hippocampal neurons.

Aliases: ARHG7 antibody, ARHG7_HUMAN antibody, ARHGEF 7 antibody, Arhgef7 antibody, Beta pix antibody, Beta-Pix antibody, betaPix antibody, betaPix-b antibody, betaPix-c antibody, Cool antibody, COOL-1 antibody, COOL1 antibody, DKFZp686C12170 antibody, DKFZp761K1021 antibody, KIAA0142 antibody, KIAA0412 antibody, mKIAA0142 antibody, Nbla10314 antibody, P50 antibody, P50BP antibody, p85 antibody, P85COOL1 antibody, P85SPR antibody, PAK interacting exchange factor beta antibody, PAK-interacting exchange factor beta antibody, PAK3 antibody, Pak3bp antibody, PIX antibody, PIXB antibody, Rho guanine nucleotide exchange factor (GEF) 7 antibody, Rho guanine nucleotide exchange factor (GEF) 7b antibody, Rho guanine nucleotide exchange factor (GEF7) antibody, Rho guanine nucleotide exchange factor 7 antibody, SH3 domain containing proline rich protein antibody

UniProt: Q14155

Pathways: EGFR Signaling Pathway, Neurotrophin Signaling Pathway, EGFR Downregulation