Ribonuclease H1 antibody (AA 73-185)

Catalog No. ABIN7168103

This Rabbit Polyclonal antibody specifically detects Ribonuclease H1 in WB, ELISA and IHC. It exhibits reactivity toward Human.

Quick Overview for Ribonuclease H1 antibody (AA 73-185) (ABIN7168103)

Target: Ribonuclease H1 (RNASEH1)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Ribonuclease H1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-Ribonuclease H1 Antibody

Binding Specificity: AA 73-185

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Ribonuclease H1 protein (73-185AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:500-1:5000, IHC:1:200-1:500,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for Ribonuclease H1

Target: Ribonuclease H1 (RNASEH1)

Alternative Name: RNASEH1

Background:

Background: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids (PubMed:10497183). Plays a role in RNA polymerase II (RNAp II) transcription termination by degrading R-loop RNA-DNA hybrid formation at G-rich pause sites located downstream of the poly(A) site and behind the elongating RNAp II (PubMed:21700224).

Aliases: RNASEH1 antibody, RNH1 antibody, Ribonuclease H1 antibody, RNase H1 antibody, EC 3.1.26.4 antibody, Ribonuclease H type II antibody

UniProt: O60930