RTCD1 antibody (AA 167-379)

Catalog No. ABIN7168269

The Rabbit Polyclonal anti-RTCD1 antibody has been validated for ELISA and IHC. It is suitable to detect RTCD1 in samples from Human.

Quick Overview for RTCD1 antibody (AA 167-379) (ABIN7168269)

Target: RTCD1 (RNA terminal Phosphate Cyclase Domain 1 (RTCD1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RTCD1 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Product Details anti-RTCD1 Antibody

Binding Specificity: AA 167-379

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human RNA 3\'-terminal phosphate cyclase protein (167-379AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for RTCD1

Target: RTCD1 (RNA terminal Phosphate Cyclase Domain 1 (RTCD1))

Alternative Name: RTCA

Background:

Background: Catalyzes the conversion of 3\'-phosphate to a 2\',3\'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP, (B) transfer of adenylate to an RNA-N3\'P to produce RNA-N3\'PP5\'A, (C) and attack of the adjacent 2\'-hydroxyl on the 3\'-phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing.

Aliases: RTCA antibody, RPC antibody, RPC1 antibody, RTC1 antibody, RTCD1 antibody, RNA 3'-terminal phosphate cyclase antibody, RNA cyclase antibody, RNA-3'-phosphate cyclase antibody, EC 6.5.1.4 antibody, RNA terminal phosphate cyclase domain-containing protein 1 antibody, RTC domain-containing protein 1 antibody

UniProt: O00442